ShortageSignal

Register · discontinuations

Product discontinuations

Where a supply notice records a product being withdrawn for good rather than temporarily short — a permanent market exit. Each row links to the notice that reported it. England-first; UK-wide where the source is.

RecordedProductReferenceSource
25 Aug 2026Medicine Supply Notification: Beclometasone dipropionate (Clenil Modulite®) 50micrograms/dose and 250 micrograms/dose inhalersMSN/2026/038notice
25 Aug 2026Medicine Supply Notification: Formoterol fumarate dihydrate (Atimos Modulite®) 12micrograms/dose inhalerMSN/2026/039notice
30 Jul 2026Medicine Supply Notification: Voltarol® Ophtha and Voltarol® Ophtha Multidose eye dropsMSN/2026/034notice
23 Jul 2026Medicine Supply Notification: Nifedipine 10mg, 20mg, 30mg and 60mg modified-release tabletsMSN/2026/033notice
04 Jun 2026Medicine Supply Notification: Rivastigmine 4.6mg/24hours and 9.5mg/24hours transdermal patches – updatedMSN/2025/062notice
30 Mar 2026Medicine Supply Notification: Chlordiazepoxide 5mg and 10mg capsulesMSN/2026/021notice
10 Feb 2026Medicine Supply Notification: Sulfadiazine silver (Flamazine®) 1% creamMSN/2026/007notice
15 Jan 2026Discontinuation of Subutex® and Suboxone® tabletsnotice
15 Jan 2026Medicine Supply Notification: Buprenorphine/naloxone (Suboxone® ) 2mg/500microgram and 8mg/2mg sublingual tabletsMSN/2026/002notice
13 Jan 2026Discontinuation of Subutex® and Suboxone® tabletsnotice
08 Jan 2026Medicine Supply Notification: Rivastigmine 4.6mg/24hours and 9.5mg/24hours transdermal patches – updatedMSN/2025/062notice
29 Dec 2025Medicine Supply Notification: Hypurin® Porcine 30/70 Mix (insulin isophane biphasic porcine) 100units/ml suspension for injection 3ml cartridgesMSN/2025/073notice
10 Dec 2025Medicine Supply Notification: Tresiba® (insulin degludec) FlexTouch® 100units/ml solution for injection 3ml prefilled pens - updatedMSN/2023/053notice
20 Oct 2025Medicine Supply Notification: Mometasone (Asmanex Twisthaler®) 200micrograms/dose dry powder and 400micrograms/dose dry powder inhalersMSN/2025/057notice
15 Oct 2025Medicine Supply Notification: Exenatide (Bydureon® BCise® ) 2mg/0.85ml prolonged-release suspension for injection pre-filled penMSN/2025/054notice
18 Sep 2025Medicine Supply Notification: Admelog® (insulin lispro)MSN/2025/052notice
14 Aug 2025Updated Medicine Supply Notification: Levemir® (insulin detemir) FlexPen® 100units/ml solution for injection 3ml pre-filled pens and Levemir® Penfill 100units/ml solution for injection 3ml cartridgesMSN/2025/036notice
06 Aug 2025Medicine Supply Notification: Estradiol (Progynova® TS) 50micrograms/24hours and 100micrograms/24hours transdermal patchesMSN/2025/048notice
23 Jul 2025Medicine Supply Notification: Vials of Humulin® I, Humulin® S, Humulin® M3, and Humalog® Mix25 are being discontinued.MSN/2025/045notice
23 Jul 2025Medicine Supply Notification: Vial presentations of Hypurin® Porcine Isophane, Hypurin® Porcine Neutral and Hypurin® Porcine 30/70 Mix are being discontinuedMSN/2025/046notice
04 Jul 2025Medicine Supply Notification: Salbutamol 100micrograms/dose breath actuated inhalers CFC freeMSN/2025/041notice
11 Apr 2025Medicine Supply Notification: Galantamine 8mg, 16mg and 24mg modified-release capsulesMSN/2025/022notice
07 Apr 2025Medicine Supply Notification: Triamcinolone acetonide 10mg/ml (Adcortyl® multi-dose vial) and 40mg/ml (Kenalog® vials) suspension for injectionMSN/2025/021notice
17 Mar 2025National Patient Safety Alert: Discontinuation of Promixin® (colistimethate) 1-million unit powder for nebuliser solution unit dose vialsNatPSA/2025/001/DHSCnotice
09 Jan 2025Medicine Supply Notification: Apomorphine hydrochloride (APO-go® PFS) 50mg/10ml solution for infusion pre-filled syringesMSN/2025/002notice
07 Jan 2025Medicine Supply Notification: NovoRapid® (insulin aspart) FlexTouch® 100units/ml solution for injection 3ml pre-filled pens-UpdatedMSN/2024/103notice
12 Dec 2024Medicine Supply Notification: Insulatard® (isophane insulin, human) Penfill® 100units/ml suspension for injection 3ml cartridgesMSN/2024/112notice
03 Dec 2024Medicine Supply Notification: Coal tar extract (Neutrogena® T/Gel® Therapeutic) 2% shampooMSN/2024/111notice
20 Nov 2024Medicine Supply Notification: Levobunolol (Betagan®) 0.5% eye drops 0.4ml unit dose preservative freeMSN/2024/108notice
07 Oct 2024Medicine Supply Notification: Trandate® (labetalol) 50mg tabletsMSN/2024/101notice
07 Oct 2024Medicine Supply Notification: Sodium fusidate (Fucidin® ) 250mg tablets and fusidic acid (Fucidin® ) 250mg/5ml oral suspensionMSN/2024/107notice
29 May 2024Medicine Supply Notification: Somatropin (NutropinAq® ) 10mg/2ml solution for injection cartridges Somatropin (Humatrope® ) 6mg, 12mg and 24mg powder and solvent for solution for injection cartridges - UpdatedMSN/2024/064notice
08 May 2024Medicine Supply Notification: Pabrinex® (Vitamins B and C) Intravenous and Intramuscular High Potency solution for injection ampoules - UpdatedMSN/2024/038notice
08 May 2024Medicine Supply Notification: Pabrinex® (Vitamins B and C) Intravenous and Intramuscular High Potency solution for injection ampoules - UpdatedMSN/2024/038notice
25 Apr 2024Medicine Supply Notification: Mesalazine (Asacol® ) 400mg MR gastro-resistant tabletsMSN/2024/048notice
03 Apr 2024Medicine Supply Notification: Pabrinex® (Vitamins B and C) Intravenous and Intramuscular High Potency solution for injection ampoulesMSN/2024/038notice
21 Mar 2024Medicine Supply Notification: Levemir InnoLet® (insulin detemir) 100units/ml solution for injection 3ml pre-filled disposable devicesMSN/2024/033notice
21 Mar 2024Medicine Supply Notification: Insulatard® InnoLet® (insulin isophane human) 100units/ml suspension for injection 3ml pre-filled disposable devicesMSN/2024/032notice
18 Mar 2024Medicine Supply Notification: Supply issues with multiple GLP-1 RA productsMSN/2024/031notice
04 Mar 2024Medicine Supply Notification: Fiasp® FlexTouch® (insulin aspart) 100units/ml solution for injection 3ml pre-filled pens - updatedMSN/2024/027notice
21 Dec 2023Medicine Supply Notification: Testosterone (Testim® ) 50mg/5g transdermal gel unit dose tubesMSN/2023/118notice
28 Nov 2023Medicine Supply Notification: Fluticasone 400microgram/unit dose nasal dropsMSN/2023/108notice
12 Oct 2023Medicine Supply Notification: Pancrease® HL gastro-resistant capsulesMSN/2023/095notice
21 Feb 2023Medicine Supply Notification: Dalteparin (Fragmin® ) 10,000units/4ml solution for injection ampouleMSN/2023/021notice
17 Jan 2023Medicine Supply Notification: Various Insuman Insulin preparations discontinued - UpdatedMSN/2023/002notice
21 Dec 2022Medicine Supply Notification: Dalteparin (Fragmin® ) 10,000units/1ml solution for injection ampouleMSN/2022/109notice
12 Oct 2022Medicine Supply Notification: Prochlorperazine (Stemetil®) 5mg/5ml SyrupMSN/2022/085notice
17 Aug 2022Medicine Supply Notification: Acebutolol (Sectral® )100mg and 200mg capsules and 400mg tabletsMSN/2021/051notice
11 Aug 2022Medicine Supply Notification: Disopyramide 150mg capsulesMSN/2022/068notice
08 Aug 2022Medicine Supply Notification: Insulin isophane biphasic human 50/50 (Insuman® Comb 50) 100units/ml suspension for injection 3ml cartridgeMSN/2022/067notice
14 Jul 2022Medicine Supply Notification: Paroxetine (Seroxat®) 20mg/10ml oral suspensionMSN/2022/063notice
26 May 2022Medicine Supply Notification: Colestipol (Colestid® ) orange and plain 5g granules sachetsMSN/2022/051notice
13 Apr 2022Medicine Supply Notification: Triamterene 50mg / furosemide 40mg (Frusene® ) tabletsMSN/2022/033notice
19 Jan 2022Medicine Supply Notification: Bambuterol (Bambec® ) 10mg TabletsMSN/2022/002notice
08 Nov 2021Medicine Supply Notification: DDAVP (Desmopressin) 0.01% w/v (100 micrograms/ml) intranasal solution - Updatednotice
01 Nov 2021Medicine Supply Notification: Acebutolol (Sectral) 100mg capsulesMSN/2021/052notice
13 Sep 2021Medicine Supply Notification: Metformin 500mg/5ml oral solutionMSN/2021/045notice
29 Apr 2021Medicine Supply Notification: Elleste Solo MX 40 and 80 transdermal patchesMSN/2021/024notice
18 Mar 2021Medicine Supply Notification: Irbesartan/ hydrochlorothiazide 150mg/12.5mg tablets - UpdateMSN/2021/014notice

A discontinuation is reported by its source; ShortageSignal re-expresses and dates it, and keeps it on the record permanently. See the full shortage register or the open API (event type product_discontinued).