Data may be out of date. Our scheduled checks are behind: the last successful check of the sources finished 20 Oct 2026, 21:00 UTC (10 days ago), more than 36 hours ago. Checks normally run twice daily, so figures on this page may be out of date. See the service status.
ShortageSignal

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Medicine · bench card

Apraclonidine

As of 31 Oct 2026 08:50 UTC. Status is always as stated in the latest recorded notice; the sources do not publish resolution, so nothing on this page says a medicine is back — see methodology.

Latest England noticeMSN/2025/018 Tier 2 · issued 27 Mar 2025 (583 days ago)
Expected backearly September 2025 as stated in the latest recorded notice stated date passed — no update recorded (416 days)window end 10 Sep 2025, derived from “early September 2025”
Protocolno Serious Shortage Protocol matched to this name on the NHSBSA register
Scotlandno NHS Scotland alert matched to this name (separate record)

Presentations, as stated in the latest recorded notice

Each line is re-expressed from MSN/2025/018 (27 Mar 2025): the product named, the status the source stated, and the expected-back phrase kept as written. Not the source's sentence, and not an observation of stock.

PresentationStatus, as statedExpected back, as statedStated in
Apraclonidine (Iopidine®) 5mg/ml (0.5%) eye dropsaffected product · inferred from phrasingOut of stock, as statedearly September 2025precision: early in the month · window end 10 Sep 2025, derived from “early September 2025”notice of 27 Mar 2025
Limited supplies of parallel imported apraclonidine (Iopidine®) 5mg/ml (0.5%) eye dropsparallel import named by the source · inferred from phrasingLimited supply, as stated⚠ the source line states more than one status — first stated shown— not stated for this linenotice of 27 Mar 2025
Brimonidine 0.2% eye dropsnamed by the source as remaining available · inferred from phrasingStated as available— not stated for this linenotice of 27 Mar 2025
Apraclonidine 10mg/ml (1%) preservative free unit dose eye dropsnamed by the source as remaining available · inferred from phrasingStated as available— not stated for this linenotice of 27 Mar 2025

Protocol in force

No Serious Shortage Protocol matched to this name is in force on the NHSBSA register. Matching is by name until identifier coding lands.

Named in the source as remaining available

  • Brimonidine 0.2% eye drops — named by the source as remaining available (inferred from phrasing)
  • Apraclonidine 10mg/ml (1%) preservative free unit dose eye drops — named by the source as remaining available (inferred from phrasing)

Only names the source itself listed, as it listed them (source post ↗). No substitution, dosing or counselling advice is given here or implied.

Identifiers — Apraclonidine

Also known as
Apraclonidine 1% eye dps 0.25ml unit dose preservative free · Apraclonidine 5mg/ml eye drops · Iopidine 1% eye drops 0.25ml unit dose · Iopidine 5mg/ml eye drops
BNF chemical
Apraclonidine 1108020J0 — matched on a generic name
Class
Ocular diagnostic & peri-operative prepn & photodynamic tt · Miscellaneous ophthalmic preparations · Eye
SNOMED codes
3799011000001100, 3956211000001103, 3958011000001107, 42184411000001108, 45673111000001106 and 2 more
Suppliers named in the NHSBSA dataset
A A H Pharmaceuticals Ltd · Essential Pharma Ltd (from the dataset, not from the notices)

BNF chemical and SNOMED identifiers from NHSBSA Prescription Cost Analysis (Open Government Licence), matched by name (presentation name), confidence 0.90 — grouping under review where marked Release Jul 2026.

BNF SNOMED mapping, NHSBSA Copyright 2026; Prescription Cost Analysis (PCA) Monthly Administrative Data, NHSBSA Copyright 2026. This information is licenced under the terms of the Open Government Licence.

History

One supply notification on record, 27 Mar 2025. We record when a shortage is declared, not when stock returns — the source doesn't publish that. An update sharing a reference counts as one episode.

IssuedNoticeKindTierReference
27 Mar 2025Medicine Supply Notification: Apraclonidine (Iopidine® ) 5mg/ml (0.5%) eye dropsSupply notificationTier 2MSN/2025/018

Also recorded under

Bracketed names seen in this medicine's notice titles: iopidine. Grouping is by the head name in each title; brand and generic names may still sit on separate pages until identifier coding refines it — see the A–Z.

Scotland — separate record

No NHS Scotland Medicine Supply Alert Notice on record matches this name. Scotland is a separate record (all Scotland alerts); absence here is not a statement about supply in Scotland.

Last checked
20 Oct 2026 — sources are checked twice daily by scheduled jobs, not continuously
Last source change
19 Oct 2026
Latest notice captured
12 Jul 2026
Sources
Latest notice post ↗https://cpe.org.uk/our-news/medicine-supply-notification-apraclonidine-iopidine-5mg-ml-0-5-eye-drops · methodology · corrections log

Re-expressed facts with links to the source documents; roles are inferred from phrasing and flagged; fuzzy dates stay fuzzy. Not an official NHS or DHSC service and not clinical advice — in a shortage, follow the guidance issued to your pharmacy or prescriber. Absence of a record is never availability.