matched by a bracketed name recorded for this medicine — name-based until identifier coding refines it. Full protocol history →
https://shortagesignal.co.uk/medicine/estradiol
As of 06 Nov 2026 02:13 UTC. Status is always as stated in the latest recorded notice; the sources do not publish resolution, so nothing on this page says a medicine is back — see methodology.
Latest England noticeMSN/2025/048 Tier 2 · issued 06 Aug 2025 (457 days ago)
Expected backno date stated by the source in the latest recorded notice
ProtocolSSP082 in force to 08 Jan 2027 · SSP081 in force to 08 Jan 2027 · SSP080 in force to 08 Jan 2027 · SSP079 in force to 08 Jan 2027
ScotlandMSAN(2025)40 issued 19 Aug 2025 — NHS Scotland's own notice, matched by name; kept separate from England
Presentations, as stated in the latest recorded notice
Each line is re-expressed from MSN/2025/048 (06 Aug 2025): the product named, the status the source stated, and the expected-back phrase kept as written. Not the source's sentence, and not an observation of stock.
| Presentation | Status, as stated | Expected back, as stated | Stated in |
|---|---|---|---|
| Progynova® TS 50micrograms/24hours and 100micrograms/24hours transdermal patches (once weekly estradiol patches)affected product · inferred from phrasing | Discontinued, as stated | — not stated for this line | notice of 06 Aug 2025 |
| FemSeven® 50micrograms/24 hours and 100micrograms/24 hours transdermal patches (once-weekly estradiol patches)named by the source as remaining available · inferred from phrasing | Stated as available | — not stated for this line | notice of 06 Aug 2025 |
| Evorel® 50micrograms and 100micrograms and Estraderm® MX 50micrograms and 100micrograms transdermal patches (twice-weekly estradiol patches)named by the source as remaining available · inferred from phrasing | Stated as available | — not stated for this line | notice of 06 Aug 2025 |
Protocol in force
matched by a bracketed name recorded for this medicine — name-based until identifier coding refines it. Full protocol history →
matched by a bracketed name recorded for this medicine — name-based until identifier coding refines it. Full protocol history →
matched by a bracketed name recorded for this medicine — name-based until identifier coding refines it. Full protocol history →
Named in the source as remaining available
- FemSeven® 50micrograms/24 hours and 100micrograms/24 hours transdermal patches (once-weekly estradiol patches) — named by the source as remaining available (inferred from phrasing)
- Evorel® 50micrograms and 100micrograms and Estraderm® MX 50micrograms and 100micrograms transdermal patches (twice-weekly estradiol patches) — named by the source as remaining available (inferred from phrasing)
Only names the source itself listed, as it listed them (source post ↗). No substitution, dosing or counselling advice is given here or implied.
Identifiers — Estradiol
BNF chemical and SNOMED identifiers from NHSBSA Prescription Cost Analysis (Open Government Licence), matched by name (presentation name), confidence 0.90 — grouping under review where marked Release Jul 2026.
BNF SNOMED mapping, NHSBSA Copyright 2026; Prescription Cost Analysis (PCA) Monthly Administrative Data, NHSBSA Copyright 2026. This information is licenced under the terms of the Open Government Licence.
History
Notified short 13 times on record since 2021 — a recurring shortage spanning 3.7 years. We record when a shortage is declared, not when stock returns — the source doesn't publish that. An update sharing a reference counts as one episode.
Also recorded under
Bracketed names seen in this medicine's notice titles: estraderm mx, estradot, estring, femseven, lenzetto, oestrogel, progynova ts, sandrena. Grouping is by the head name in each title; brand and generic names may still sit on separate pages until identifier coding refines it — see the A–Z.
Scotland — separate record
NHS Scotland issues its own Medicine Supply Alert Notices. These match this medicine's name; they are shown beside, never added to, the England record.
- MSAN(2025)40 Estradiol (Progynova® TS) 50micrograms/24hours and 100micrograms/24hours · issued 19 Aug 2025 · valid until above noted product is being discontinued, as stated · matched by name PDF ↗
- MSAN(2025)14 Estradiol (Estradot®) 25 micrograms/24 hours, 37.5 micrograms/24 hours, 50 · issued 11 Apr 2025 · valid until various resupply dates – see below, as stated · matched by name PDF ↗
- MSAN(2024)69 Estradiol (Estradot®) 50micrograms/24 hours, 75micrograms/24 hours, and · issued 27 Dec 2024 · valid until various resupply dates – see below, as stated · matched by name PDF ↗
- MSAN(2023)25 Estradiol (FemSeven®) 75micrograms/24hours and 100micrograms/24hours · issued 19 Sep 2023 · valid until w/c 2nd October 2023, as stated · matched by name PDF ↗
- MSAN(2023)24 Estradiol valerate/medroxyprogesterone acetate (Indivina®) 1mg/5mg tablets · issued 19 Sep 2023 · valid until w/c 11th December 2023, as stated · matched by name PDF ↗
- MSAN(2023)17 Estradiol (Estradot®) 25micrograms/24 hours, 37.5micrograms/24 hours and · issued 29 Aug 2023 · valid until late September 2023, as stated · matched by name PDF ↗