As of 03 Nov 2026 16:12 UTC. Status is always as stated in the latest recorded notice; the sources do not publish resolution, so nothing on this page says a medicine is back — see methodology.
Presentations, as stated in the latest recorded notice
Each line is re-expressed from MSN/2023/057 (06 Jun 2023): the product named, the status the source stated, and the expected-back phrase kept as written. Not the source's sentence, and not an observation of stock.
| Presentation | Status, as stated | Expected back, as stated | Stated in |
|---|---|---|---|
| Insuman® Comb 25 100units/ml suspension for injection 3ml cartridges and prefilled pensaffected product · inferred from phrasing | Discontinued, as stated | — not stated for this line | notice of 06 Jun 2023 |
| Humulin® M3named by the source as remaining available · inferred from phrasing | Stated as available | — not stated for this line | notice of 06 Jun 2023 |
Protocol in force
No Serious Shortage Protocol matched to this name is in force on the NHSBSA register. Matching is by name until identifier coding lands.
Named in the source as remaining available
- Humulin® M3 — named by the source as remaining available (inferred from phrasing)
Only names the source itself listed, as it listed them (source post ↗). No substitution, dosing or counselling advice is given here or implied.
Identifiers — Insulin Isophane Biphasic Human
BNF chemical and SNOMED identifiers from NHSBSA Prescription Cost Analysis (Open Government Licence), matched by name (presentation name), confidence 0.90 — grouping under review where marked Release Sep 2026.
BNF SNOMED mapping, NHSBSA Copyright 2026; Prescription Cost Analysis (PCA) Monthly Administrative Data, NHSBSA Copyright 2026. This information is licenced under the terms of the Open Government Licence.
History
Notified short 2 times on record since 2022. We record when a shortage is declared, not when stock returns — the source doesn't publish that. An update sharing a reference counts as one episode.
| Issued | Notice | Kind | Tier | Reference |
|---|---|---|---|---|
| 06 Jun 2023 | Medicine Supply Notification: Insulin isophane biphasic human 25/75 (Insuman® Comb 25) 100units/ml suspension for injection 3ml cartridge and pre-filled Solostar pens | Supply notification | Tier 2 | MSN/2023/057 |
| 08 Aug 2022 | Medicine Supply Notification: Insulin isophane biphasic human 50/50 (Insuman® Comb 50) 100units/ml suspension for injection 3ml cartridge | Supply notification | Tier 2 | MSN/2022/067 |
Also recorded under
No other name appears in this medicine's notice titles. Grouping is by the head name in each title; brand and generic names may still sit on separate pages until identifier coding refines it — see the A–Z.
Scotland — separate record
NHS Scotland issues its own Medicine Supply Alert Notices. These match this medicine's name; they are shown beside, never added to, the England record.
- MSAN(2023)4 • Insulin isophane biphasic human 25/75 (Insuman® Comb 25) 100units/ml · issued 25 Jan 2023 · valid until discontinuation, stock to be exhausted by May 2023, as stated · matched by name PDF ↗