Data may be out of date. Our scheduled checks are behind: the last successful check of the sources finished 20 Oct 2026, 21:00 UTC (16 days ago), more than 36 hours ago. Checks normally run twice daily, so figures on this page may be out of date. See the service status.
ShortageSignal

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Medicine · bench card

Pancreatic Enzyme Replacement Therapy

As of 06 Nov 2026 08:39 UTC. Status is always as stated in the latest recorded notice; the sources do not publish resolution, so nothing on this page says a medicine is back — see methodology.

Latest England safety alertMSN/2024/054 · issued 24 May 2024 (896 days ago)
Expected backmid-August 2024 as stated in the latest recorded notice stated date passed — no update recorded (808 days)window end 20 Aug 2024, derived from “mid-August 2024”
ProtocolSSP061 in force to 08 Jan 2027 (matched because this medicine's latest notice names the protocol's product as affected)
ScotlandMSAN(2024)24 issued 13 May 2024 — NHS Scotland's own notice, matched by name; kept separate from England

Presentations, as stated in the latest recorded notice

Each line is re-expressed from MSN/2024/054 (24 May 2024): the product named, the status the source stated, and the expected-back phrase kept as written. Not the source's sentence, and not an observation of stock.

PresentationStatus, as statedExpected back, as statedStated in
Creon® 10,000 and 25,000 capsulesaffected product · inferred from phrasingLimited supply, as stated— not stated for this linenotice of 24 May 2024
Nutrizym® 22 capsulesaffected product · inferred from phrasingOut of stock, as statedmid-August 2024precision: mid-month · window end 20 Aug 2024, derived from “mid-August 2024”notice of 24 May 2024
Pancrex V® capsules and powdernamed by the source as remaining available · inferred from phrasingStated as available; cannot support an uplift in demand— not stated for this linenotice of 24 May 2024

Protocol in force

SSP061Creon® 25000 gastro-resistant capsulesin force
Valid
24 May 2024 → 08 Jan 2027 (NHSBSA register dates)
Where it applies
UK-wide
Legal category
POM
Signed protocol
Protocol and endorsement documents (NHSBSA) ↗https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/serious-shortage-protocols-ssps#SSP061%20Creon%2025000%20restriction%20FINAL%2023052024%20-%20Signed.pdf

matched because this medicine's latest notice names the protocol's product as affected — name-based until identifier coding refines it. Full protocol history →

Named in the source as remaining available

  • Pancrex V® capsules and powder — named by the source as remaining available (inferred from phrasing)

Only names the source itself listed, as it listed them (source post ↗). No substitution, dosing or counselling advice is given here or implied.

Identifiers — Pancreatic Enzyme Replacement Therapy

Grouping under review The name on this page has not been matched to one BNF chemical with enough confidence to assert it; nothing here is grouped until a reviewer confirms it.

BNF chemical and SNOMED identifiers from NHSBSA Prescription Cost Analysis (Open Government Licence), matched by name, confidence not asserted — grouping under review where marked

BNF SNOMED mapping, NHSBSA Copyright 2026; Prescription Cost Analysis (PCA) Monthly Administrative Data, NHSBSA Copyright 2026. This information is licenced under the terms of the Open Government Licence.

History

One supply notification on record, 09 May 2024. We record when a shortage is declared, not when stock returns — the source doesn't publish that. An update sharing a reference counts as one episode.

IssuedNoticeKindTierReference
24 May 2024National Patient Safety Alert: Shortage of Pancreatic enzyme replacement therapy (PERT)Safety alert—MSN/2024/054
09 May 2024Medicine Supply Notification: Pancreatic enzyme replacement therapy (PERT)Supply notification—MSN/2024/054

Also recorded under

Bracketed names seen in this medicine's notice titles: pert. Grouping is by the head name in each title; brand and generic names may still sit on separate pages until identifier coding refines it — see the A–Z.

Scotland — separate record

NHS Scotland issues its own Medicine Supply Alert Notices. These match this medicine's name; they are shown beside, never added to, the England record.

Last checked
20 Oct 2026 — sources are checked twice daily by scheduled jobs, not continuously
Last source change
19 Oct 2026
Latest notice captured
18 Jun 2024
Sources
Latest notice post ↗https://cpe.org.uk/our-news/national-patient-safety-alert-shortage-of-pancreatic-enzyme-replacement-therapy-pert · Signed protocol (NHSBSA) ↗ · methodology · corrections log

Re-expressed facts with links to the source documents; roles are inferred from phrasing and flagged; fuzzy dates stay fuzzy. Not an official NHS or DHSC service and not clinical advice — in a shortage, follow the guidance issued to your pharmacy or prescriber. Absence of a record is never availability.