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Month in review

December 2025: UK medicine shortages

Every change to the UK medicines supply that entered the public record in December 2025 — 14 events across 3 categories, each linked to its source. A fixed, citable snapshot: this page shows December 2025 and will not change as later months are added.

New supply notifications · 9

DateMedicine / noticeReference
29 Dec 2025Medicine Supply Notification: Hypurin® Porcine 30/70 Mix (insulin isophane biphasic porcine) 100units/ml suspension for injection 3ml cartridgesMSN/2025/073
23 Dec 2025Medicine Supply Notification: Clonidine (Catapres®) 100microgram tabletsMSN/2025/070
23 Dec 2025Medicine Supply Notification: Genotropin® (somatropin) 5.3 mg and 12 mg powder and solvent for solution for injectionMSN/2025/072
23 Dec 2025Medicine Supply Notification: Diamorphine 5mg, 10mg and 100mg powder for solution for injection ampoulesMSN/2025/071
19 Dec 2025Medicine Supply Notification: Nifedipine (Adipine® XL) 30mg and 60mg modified-release tabletsMSN/2025/068
19 Dec 2025Medicine Supply Notification: Latanoprost 50micrograms/ml / Timolol 5mg/ml (Fixapost® ) eye drops 0.2ml unit dose preservative freeMSN/2025/069
10 Dec 2025Medicine Supply Notification: Tresiba® (insulin degludec) FlexTouch® 100units/ml solution for injection 3ml prefilled pens - updatedMSN/2023/053
08 Dec 2025Medicine Supply Notification: Nifedipine (Fortipine® LA) 40mg modified-release tabletsMSN/2025/064
03 Dec 2025Medicine Supply Notification: Rivastigmine 4.6mg/24hours and 9.5mg/24hours transdermal patches – updatedMSN/2025/062

New Serious Shortage Protocols · 3

DateMedicine / noticeReference
19 Dec 2025Serious Shortage Protocol issuedSSP086
19 Dec 2025Serious Shortage Protocol issuedSSP085
19 Dec 2025Serious Shortage Protocol issuedSSP084

Discontinuations · 2

DateMedicine / noticeReference
29 Dec 2025Medicine Supply Notification: Hypurin® Porcine 30/70 Mix (insulin isophane biphasic porcine) 100units/ml suspension for injection 3ml cartridgesMSN/2025/073
10 Dec 2025Medicine Supply Notification: Tresiba® (insulin degludec) FlexTouch® 100units/ml solution for injection 3ml prefilled pens - updatedMSN/2023/053
← November 2025January 2026 →

Cite as: “UK Shortage Index — December 2025 in review, ShortageSignal (shortagesignal.co.uk/uk-shortage-index/2025-12), by Doctor Data Ltd.” Coverage is England-first and reflects notifications relayed publicly; the archive window means very early months may under-count resolved notices. Not an official NHS or DHSC service.